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1

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

Dehay, Benjamin, Bourdenx, Mathieu, Gorry, Philippe, Przedborski, Serge, Vila, Miquel, Hunot, Stéphane, Singleton, Andrew, Olanow, C Warren, Merchant, Kalpana M, Bezard, Erwan, Petsko, Gregory A, Meis

Journal:

The Lancet Neurology

Year:

2015

Language:

english

File:

PDF, 904 KB

english, 2015

2

Physiologie de la circulation veineuse

Boisseau, M.R., Bourdenx, V., Diard, A., Moore, N.

Journal:

EMC - Angéiologie

Year:

2008

Language:

french

File:

PDF, 906 KB

french, 2008

3

Selective autophagy as a potential therapeutic target for neurodegenerative disorders

Scrivo, Aurora, Bourdenx, Mathieu, Pampliega, Olatz, Cuervo, Ana Maria

Journal:

The Lancet Neurology

Year:

2018

Language:

english

File:

PDF, 715 KB

english, 2018

4

The VLCFA elongase gene family inArabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling

Jérôme Joubès, Sylvain Raffaele, Brice Bourdenx, Christel Garcia, Jeanny Laroche-Traineau, Patrick Moreau, Frédéric Domergue, René Lessire

Journal:

Plant Molecular Biology

Year:

2008

Language:

english

File:

PDF, 942 KB

english, 2008

5

Rapid nanoscale quantitative analysis of plant sphingolipid long-chain bases by GC-MS

Cacas, Jean-Luc, Melser, Su, Domergue, Frédéric, Joubès, Jérôme, Bourdenx, Brice, Schmitter, Jean-Marie, Mongrand, Sébastien

Journal:

Analytical and Bioanalytical Chemistry

Year:

2012

Language:

english

File:

PDF, 336 KB

english, 2012

6

Standard heparin but not LMW heparin induces a concomitant increase of t-PA and PAI-1 without modification of global fibrinolysis: Study after 60 days treatment

C. Vergnes, G. Manciet, V. Bourdenx, M.F. Roudaut, F. Lacombe, M.R. Boisseau

Journal:

Thrombosis Research

Year:

1991

Language:

english

File:

PDF, 723 KB

english, 1991

7

Fibrinolytic treatment for prosthetic heart valve thrombosis: Early and long term results experience with 55 patients

Raymond Roudaut, Thierry Labbe, Françoise Lorient Roudaut, Véronique Bourdenx, Pierre Besse, Michel Boisseau, Modeste Dallocchio

Journal:

Journal of the American College of Cardiology

Year:

1991

Language:

english

File:

PDF, 192 KB

english, 1991

8

Phosphorylation of α-Synuclein at ser120 accelerates neurodegeneration

Bourdenx, Mathieu

Journal:

Movement Disorders

Year:

2013

Language:

english

File:

PDF, 42 KB

english, 2013

9

DNA as the next digital information storage support

Bourdenx, Mathieu

Journal:

Movement Disorders

Year:

2013

Language:

english

File:

PDF, 43 KB

english, 2013

10

Allograft of stem cell-derived dopaminergic neurons for Parkinson's disease

Bourdenx, Mathieu

Journal:

Movement Disorders

Year:

2013

Language:

english

File:

PDF, 45 KB

english, 2013

11

Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and l-DOPA-induced dyskinesia

Bourdenx, Mathieu, Nilsson, Anna, Wadensten, Henrik, Fälth, Maria, Li, Qin, Crossman, Alan R., Andrén, Per E., Bezard, Erwan

Journal:

Neurobiology of Disease

Year:

2014

Language:

english

File:

PDF, 571 KB

english, 2014

12

In England Now

Bourdenx, Mathieu, Nilsson, Anna, Wadensten, Henrik, Fälth, Maria, Li, Qin, Crossman, Alan R., Andrén, Per E., Bezard, Erwan

Journal:

Year:

1986

Language:

english

File:

PDF, 176 KB

english, 1986

13

The Impact of Water Deficiency on Leaf Cuticle Lipids of Arabidopsis

Kosma, D. K., Bourdenx, B., Bernard, A., Parsons, E. P., Lu, S., Joubes, J., Jenks, M. A.

Journal:

PLANT PHYSIOLOGY

Year:

2009

Language:

english

File:

PDF, 1.31 MB

english, 2009

14

Arythmies chez les patients hémodialysés : caractérisation à l’aide d’un enregistreur Holter implantable

Sacher, F., Bénard, A., Bories, P., Bourdenx, J., Delmas, Y., Haddj-Elmrabet, A., Keller, A., Lavainne, F., Ott, J., Seniuta, P., Hannedouche, T., Combe, C.

Journal:

Néphrologie & Thérapeutique

Year:

2014

Language:

french

File:

PDF, 64 KB

french, 2014

15

Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-Dopa-Induced Dyskinesia

Engeln, Michel, Bastide, Matthieu F., Toulmé, Estelle, Dehay, Benjamin, Bourdenx, Mathieu, Doudnikoff, Evelyne, Li, Qin, Gross, Christian E., Boué-Grabot, Eric, Pisani, Antonio, Bezard, Erwan, Fernagu

Journal:

Biological Psychiatry

Year:

2014

Language:

english

File:

PDF, 2.23 MB

english, 2014

16

Down-regulating α-synuclein for treating synucleopathies

Bourdenx, Mathieu, Dehay, Benjamin, Bezard, Erwan

Journal:

Movement Disorders

Year:

2014

Language:

english

File:

PDF, 123 KB

english, 2014

17

Overexpression of Arabidopsis ECERIFERUM1 Promotes Wax Very-Long-Chain Alkane Biosynthesis and Influences Plant Response to Biotic and Abiotic Stresses

Bourdenx, B., Bernard, A., Domergue, F., Pascal, S., Leger, A., Roby, D., Pervent, M., Vile, D., Haslam, R. P., Napier, J. A., Lessire, R., Joubes, J.

Journal:

PLANT PHYSIOLOGY

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

18

D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly

Barroso-Chinea, Pedro, Thiolat, Marie-Laure, Bido, Simone, Martinez, Audrey, Doudnikoff, Evelyne, Baufreton, Jérôme, Bourdenx, Mathieu, Bloch, Bertrand, Bezard, Erwan, Martin-Negrier, Marie-Laure

Journal:

Neurobiology of Disease

Year:

2015

Language:

english

File:

PDF, 1.98 MB

english, 2015

19

Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies

Bourdenx, Mathieu, Koulakiotis, Nikolaos Stavros, Sanoudou, Despina, Bezard, Erwan, Dehay, Benjamin, Tsarbopoulos, Anthony

Journal:

Progress in Neurobiology

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

20

Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression

Bourdenx, Mathieu, Dovero, Sandra, Engeln, Michel, Bido, Simone, Bastide, Matthieu F., Dutheil, Nathalie, Vollenweider, Isabel, Baud, Laetitia, Piron, Camille, Grouthier, Virginie, Boraud, Thomas, Por

Journal:

Acta Neuropathologica Communications

Year:

2015

Language:

english

File:

PDF, 2.70 MB

english, 2015

21

The Impact of Water Deficiency on Leaf Cuticle Lipids of Arabidopsis

Dylan K. Kosma, Brice Bourdenx, Amélie Bernard, Eugene P. Parsons, Shiyou Lü, Jérôme Joubès and Matthew A. Jenks

Journal:

PLANT PHYSIOLOGY

Year:

2009

Language:

english

File:

PDF, 2.61 MB

english, 2009

22

Nanoparticles restore lysosomal acidification defects: Implication for Parkinson and other lysosomal-related diseases

Bourdenx, Mathieu, Daniel, Jonathan, Genin, Emilie, Soria, Federico N., Blanchard-Desce, Mireille, Bezard, Erwan, Dehay, Benjamin

Journal:

Year:

2016

Language:

english

File:

PDF, 2.14 MB

english, 2016

23

What lysosomes actually tell us about Parkinson’s disease?

Bourdenx, Mathieu, Dehay, Benjamin

Journal:

Ageing Research Reviews

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

24

Overexpression of Arabidopsis ECERIFERUM1 Promotes Wax Very-Long-Chain Alkane Biosynthesis and Influences Plant Response to Biotic and Abiotic Stresses

Brice Bourdenx, Amélie Bernard, Frédéric Domergue, Stéphanie Pascal, Amandine Léger, Dominique Roby, Marjorie Pervent, Denis Vile, Richard P. Haslam, Johnathan A. Napier, René Lessire and Jérôme Joubè

Journal:

PLANT PHYSIOLOGY

Year:

2011

Language:

english

File:

PDF, 3.55 MB

english, 2011

25

Alpha-synuclein inoculation initiates a neurodegenerative cascade in nontransgenic mice

Bourdenx, Mathieu

Journal:

Movement Disorders

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

26

Targeting α-synuclein: Therapeutic options

Dehay, Benjamin, Decressac, Mickael, Bourdenx, Mathieu, Guadagnino, Irene, Fernagut, Pierre-Olivier, Tamburrino, Anna, Bassil, Fares, Meissner, Wassilios G., Bezard, Erwan

Journal:

Movement Disorders

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

27

Early prenatal exposure to MPTP does not affect nigrostrial neurons in macaque monkey

Bourdenx, Mathieu, Dovero, Sandra, De DeurwAerdère, Philippe, Li, Qin, Bezard, Erwan

Journal:

Year:

2016

Language:

english

File:

PDF, 170 KB

english, 2016

28

Le Blood Volume Monitoring (BVM®) améliore-t-il la tolérance tensionnelle per-dialytique ?

Bourdenx, J., Pommereau, A., Martinez, C., Martin-Dupont, P., Bouchet, J.-L., Bachelet, T.

Journal:

Néphrologie & Thérapeutique

Year:

2016

Language:

french

File:

PDF, 61 KB

french, 2016

29

Identification des différents profils de Blood Volume Monitoring (BVM®) en pratique

Bourdenx, J., Pommereau, A., Martin-Dupont, P., Martinez, C., Bouchet, J.-L., Bachelet, T.

Journal:

Néphrologie & Thérapeutique

Year:

2016

Language:

french

File:

PDF, 61 KB

french, 2016

30

Stratégie de déploiement du blood volume monitoring (BVM®) à l’échelle d’un centre : à la recherche du VSR cible

Bourdenx, J., Pommereau, A., Martin-Dupont, P., Martinez, C., Bouchet, J.L., Perrone, B., Bachelet, T.

Journal:

Néphrologie & Thérapeutique

Year:

2016

Language:

french

File:

PDF, 66 KB

french, 2016

31

Utilisation de dialysats tampon-citrate comme alternative à la tinzaparine sodique chez les patients anticoagulés par voie systémique

Bachelet, T., Pommereau, A., Martinez, C., Martin-Dupont, P., Bouchet, J.-L., Bourdenx, J.

Journal:

Néphrologie & Thérapeutique

Year:

2016

Language:

french

File:

PDF, 73 KB

french, 2016

32

Place des « outils embarqués » (BVM et BTM) dans la prise en charge de la surcharge hydro-sodée

Bourdenx, J.-P., Fartoux, L.

Journal:

Néphrologie & Thérapeutique

Year:

2016

Language:

french

File:

PDF, 283 KB

french, 2016

33

Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model

Bourdenx, Mathieu, Dovero, Sandra, Thiolat, Marie-Laure, Bezard, Erwan, Dehay, Benjamin

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.39 MB

english, 2017

34

In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains

Cavaliere, Fabio, Cerf, Loic, Dehay, Benjamin, Ramos-Gonzalez, Paula, De Giorgi, Francesca, Bourdenx, Mathieu, Bessede, Alban, Obeso, Jose A., Matute, Carlos, Ichas, François, Bezard, Erwan

Journal:

Neurobiology of Disease

Year:

2017

Language:

english

File:

PDF, 4.02 MB

english, 2017

35

Involvement of the bed nucleus of the stria terminalis in L-Dopa induced dyskinesia

Bastide, Matthieu F., Glangetas, Christelle, Doudnikoff, Evelyne, Li, Qin, Bourdenx, Mathieu, Fernagut, Pierre-Olivier, Dumont, Éric C., Georges, François, Bézard, Erwan

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 5.35 MB

english, 2017

36

In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson’s disease

Chansel-Debordeaux, L, Bourdenx, M, Dovero, S, Grouthier, V, Dutheil, N, Espana, A, Groc, L, Jimenez, C, Bezard, E, Dehay, B

Journal:

Year:

2017

Language:

english

File:

PDF, 2.66 MB

english, 2017

37

Cardiac Rhythm Disturbances in Hemodialysis Patients

Sacher, Frederic, Jesel, Laurence, Borni-Duval, Claire, De Precigout, Valerie, Lavainne, Frédéric, Bourdenx, Jean-Philippe, Haddj-Elmrabet, Atman, Seigneuric, Bruno, Keller, Adrien, Ott, Julien, Savel

Journal:

JACC: Clinical Electrophysiology

Year:

2017

Language:

english

File:

PDF, 2.90 MB

english, 2017

38

Autophagie et cerveau

Bourdenx, Mathieu, Dehay, Benjamin

Journal:

médecine/sciences

Year:

2017

Language:

french

File:

PDF, 1.25 MB

french, 2017

39

Exosomes, an Unmasked Culprit in Neurodegenerative Diseases

Soria, Federico N., Pampliega, Olatz, Bourdenx, Mathieu, Meissner, Wassilios G., Bezard, Erwan, Dehay, Benjamin

Journal:

Frontiers in Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.14 MB

english, 2017

40

Lysosomes and Î±-synuclein form a dangerous duet leading to neuronal cell death

Bourdenx, Mathieu, Bezard, Erwan, Dehay, Benjamin

Journal:

Frontiers in Neuroanatomy

Year:

2014

Language:

english

File:

PDF, 542 KB

english, 2014

41

Systemic gene delivery to the central nervous system using Adeno-associated virus

Bourdenx, Mathieu, Dutheil, Nathalie, Bezard, Erwan, Dehay, Benjamin

Journal:

Frontiers in Molecular Neuroscience

Year:

2014

Language:

english

File:

PDF, 590 KB

english, 2014

42

Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats

Chansel-Debordeaux, Lucie, Bourdenx, Mathieu, Dutheil, Nathalie, Dovero, Sandra, Canron, Marie-Helene, Jimenez, Clement, Bezard, Erwan, Dehay, Benjamin

Journal:

Human Gene Therapy Methods

Year:

2018

File:

PDF, 2.10 MB

2018

43

Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats

Chansel-Debordeaux, Lucie, Bourdenx, Mathieu, Dutheil, Nathalie, Dovero, Sandra, Canron, Marie-Helene, Jimenez, Clement, Bezard, Erwan, Dehay, Benjamin

Journal:

Human Gene Therapy Methods

Year:

2018

Language:

english

File:

PDF, 2.10 MB

english, 2018

44

Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia

Geier, Ethan G., Bourdenx, Mathieu, Storm, Nadia J., Cochran, J. Nicholas, Sirkis, Daniel W., Hwang, Ji-Hye, Bonham, Luke W., Ramos, Eliana Marisa, Diaz, Antonio, Van Berlo, Victoria, Dokuru, Deepika,

Journal:

Acta Neuropathologica

Year:

2018

Language:

english

File:

PDF, 3.35 MB

english, 2018

45

Proteome-wide analysis of chaperone-mediated autophagy targeting motifs

Kirchner, Philipp, Bourdenx, Mathieu, Madrigal-Matute, Julio, Tiano, Simoni, Diaz, Antonio, Bartholdy, Boris A., Will, Britta, Cuervo, Ana Maria, Simonsen, Anne

Journal:

Year:

2019

Language:

english

File:

PDF, 6.02 MB

english, 2019

46

Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates

Arotcarena, Marie-Laure, Dovero, Sandra, Prigent, Alice, Bourdenx, Mathieu, Camus, Sandrine, Porras, Gregory, Thiolat, Marie-Laure, Tasselli, Maddalena, Aubert, Philippe, Kruse, Niels, Mollenhauer, Br

Journal:

Year:

2020

File:

PDF, 1.66 MB

2020

47

Identification of distinct pathological signatures induced by patient-derived Î±-synuclein structures in nonhuman primates

Bourdenx, M., Nioche, A., Dovero, S., Arotcarena, M.-L., Camus, S., Porras, G., Thiolat, M.-L., Rougier, N. P., Prigent, A., Aubert, P., Bohic, S., Sandt, C., LaferriÃ¨re, F., Doudnikoff, E., Kruse, N

Journal:

Science Advances

Year:

2020

File:

PDF, 8.57 MB

2020